Figure 6. Kaiso Depleted PC-3 RFP cells show decreased in vivo metastasis.
A. RFP sh-scr and sh-Kaiso cells in mice (n=7) were inoculated through intra cardiac injection and tumor formation/metastasis was measured by RFP expression over 30 days. B. X-Ray Image is representative of the tibia from mice after 30 days, and H&E image is representative of tumors excised from bone tibia After 30 days, C. Schematic of EGFR-Kaiso-miR-200 regulation in epithelial and mesenchymal prostate cancer cells.