Figure 1.

Plasma corticosterone and body composition analysis from Cvs and three months post Cvs mice. Experimental protocol: C57BL/6 male mice were exposed to chronic variable stress (Cvs) for 15 days or to no intervention (Ctrl) (A). Mice underwent respective in vivo and ex vivo analyses right after Cvs intervention or three months post Cvs intervention (Cvs3m) and compared to the age-matched controls (Ctrl and Ctrl3m, respectively). Corticosterone (Cort) levels in plasma from mice fasted for 4 h (B) n = 10–12. Body weight, lean and fat mass data from Cvs (C–E) and Cvs3m mice (F–H) n = 9–12. Data presented as means ± s.e.m. Statistical analyses were done by two-tailed unpaired Student's t-test (B–G). **p < 0.01.