Figure 5.
Enhanced liver triglyceride (TAG) content positively correlates with FGF21 secretion in mice three months post Cvs. Liver TAG content from Cvs and three months post Cvs (Cvs3m) mice (A) compared to the age-matched controls (Ctrl and Ctrl3m, respectively) n = 9–10. mRNA expression of gene associated with lipogenesis (B), fatty acid uptake (C), lipolysis (D) and fat oxidation (E) from Cvs3m and Ctrl3m mice n = 6. Plasma level of FGF21 (F) n = 8–9 and correlation analysis of plasma FGF21 and liver TAG content (G) n = 6–7. Values are means ± s.e.m. Statistical analyses were done by two-tailed unpaired Student's t-test (B–E) or by Two-Way ANOVA followed by Bonferroni post hoc (A and F). *p < 0.05, **p < 0.01. r is representing Pearson correlation.