Figure 6.

Schematic diagram depicting a unifying model for the metabolic benefits of bariatric surgery, PLA2G1B inactivation, and bile diversion. This diagram depicts the impact of bariatric surgery and bile diversion in promoting LPCAT3 activity to reduce levels of LPC and its metabolites lysophosphatidic acid (LPA) and choline whereas PLA2G1B inactivation reduces these metabolites by reducing their production, both of which are expected to reduce obesity, improve diabetes, and reduce atherosclerosis.