Table 4.
Univariate* | Multivariate** | |||
---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | |
Primary outcome | ||||
Total CV events | 2.35 (1.77–3.13) | <0.001 | 2.93 (1.95–4.39) | <0.001 |
Secondary outcome | ||||
CV or cerebrovascular death | 41.75 (5.39–323386) | 0.004 | 22.89 (2.16–242.55) | 0.009 |
Nonfatal myocardial infarction | 1.96 (0.84–4.58) | 0.120 | 2.62 (0.80–8.59) | 0.112 |
Nonfatal stroke | 3.91 (0.79–19.35) | 0.085 | 1.56 (0.06–38.62) | 0.786 |
Acute heart failure related hospitalization | 3.90 (1.46–10.39) | 0.007 | 5.16 (1.10–24.32) | 0.038 |
CV = cardiovascular.
*Non-adjusting.
**Adjusting for significant variables in univariate analysis, which including age, gender, body mass index, serum creatinine, estimated glomerular filtration rate, high-density lipoprotein, low-density lipoprotein, hemoglobin, fasting glucose, high sensitivity C-reactive protein, N-terminal pro-brain natriuretic peptide, systolic blood pressure, history of hypertension, smoking and diabetes, family history of premature CAD.