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. 2018 Sep 26;8:14410. doi: 10.1038/s41598-018-32210-x

Table 4.

Univariate and multivariable logistic Cox-proportional regression analysis models for clinical outcomes.

Univariate* Multivariate**
HR (95% CI) p HR (95% CI) p
Primary outcome
Total CV events 2.35 (1.77–3.13) <0.001 2.93 (1.95–4.39) <0.001
Secondary outcome
CV or cerebrovascular death 41.75 (5.39–323386) 0.004 22.89 (2.16–242.55) 0.009
Nonfatal myocardial infarction 1.96 (0.84–4.58) 0.120 2.62 (0.80–8.59) 0.112
Nonfatal stroke 3.91 (0.79–19.35) 0.085 1.56 (0.06–38.62) 0.786
Acute heart failure related hospitalization 3.90 (1.46–10.39) 0.007 5.16 (1.10–24.32) 0.038

CV = cardiovascular.

*Non-adjusting.

**Adjusting for significant variables in univariate analysis, which including age, gender, body mass index, serum creatinine, estimated glomerular filtration rate, high-density lipoprotein, low-density lipoprotein, hemoglobin, fasting glucose, high sensitivity C-reactive protein, N-terminal pro-brain natriuretic peptide, systolic blood pressure, history of hypertension, smoking and diabetes, family history of premature CAD.