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. 2018 Sep 26;9:3930. doi: 10.1038/s41467-018-06408-6

Table 2.

Network characteristics

Characteristic Asymptomatic, n = 1378 MS, n = 115 P-valuea
Network structure b
Size, median [IQR] 8.00 [6.00, 12.00] 8.00 [5.00, 11.50] 0.130
Density, median [IQR] 67.00 [50.00, 89.00] 69.00 [53.00, 90.00] 0.170
Constraint, median [IQR] 44.00 [37.72, 53.03] 44.71 [38.19, 56.17] 0.315
Effective size, median [IQR] 4.00 [2.80, 5.25] 3.55 [2.50, 5.07] 0.053
Maximum degree, median [IQR] 5.00 [4.00, 7.00] 5.00 [4.00, 8.00] 0.987
Mean degree, median [IQR] 4.00 [2.80, 5.00] 4.00 [2.50, 5.40] 0.493
Network Composition–General c
Percent kin, median [IQR] 43 [30, 62] 50 [33,67] 0.205
Percent who are supportive, median [IQR] 38 [25, 50] 40 [21,50] 0.561
Standard deviation of age, median [IQR] 12.76 [10.04, 15.38] 12.98 [10.54, 16.89] 0.161
Diversity of sex, median [IQR] 0.89 [0.64, 0.96] 0.82 [0.64, 0.96] 0.108
Diversity of race, median, Percentile {90th, 95th, 99th,100th}d 0 {0.44, 0.55, 0.72, 1.20} 0 {0.41, 0.59, 0.77, 0.77} 0.046
Percent contacted weekly or less often, median [IQR] 67 [50, 80] 67 [45, 80] 0.896
Percent who have been known for less than 6 years, median [IQR] 20 [0, 43] 12 [0, 33] 0.001
Percent who live more than 15 miles away, median [IQR] 33 [17, 50] 33 [20, 56] 0.514
Network Composition–Health Habits e
Percent who smoke, median [IQR] 0 [0, 20] 0 [0, 40] 0.164
Percent who do not exercise, median [IQR] 33 [14, 54] 25 [10, 50] 0.068
Percent who do not take medications regularly, median, Percentile {90th, 95th, 99th,100th} 0 {0, 14, 33, 100} 0 {0, 17, 24, 50} 0.709
Percent who do not go to doctor’s appointments, median, Percentile {90th, 95th, 99th,100th} 0 {0, 12, 25, 100} 0 {0, 15, 48, 100} 0.314
Percent who have a negative influence on health, median, Percentile {90th, 95th, 99th,100th} 0 {29, 46, 71, 100} 0 {20, 33, 78, 100} 0.150

aP-values calculated using Wilcoxon signed-rank test

bNetwork structure is quantified into graph theoretic statistics. See definitions in Methods

cNetwork composition–General is the range of characteristics of people around the participant. See definitions in Methods

dPercentile is used to better understand the right-skewed distribution of the variables of race and certain health habits

eNetwork composition–Health Behavior is the range of health habits of people around the participant