Figure 5.

Blocking of voltage-gated ion channels using a high dose of nifedipine (Nf) during dynamic cultures led to significant reductions in 8 out of 11 measurements performed. No measurements were significantly different between the dynamic high-dose group and any of the static groups. Circle (for dynamic cultures) and triangles (for static cultures) represent individual data points. Black horizontal lines represent significant differences between groups (significance for p-value less than 0.05). Full details of statistical results, including means, standard deviations (s.d.) and p-values, are reported in the electronic supplementary material, tables S1–S10.