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. 2018 Sep 26;9:3945. doi: 10.1038/s41467-018-06234-w

Table 2.

The results of genetic correlation between the lateral ventricular volume and anthropometric traits, brain volumes, neurological and psychiatric diseases and personality traits

Category Phenotype PMID N rg SE P
Anthropometric
Height 20881960 133,859 −0.135 0.049 5.70E−03
Infant head circumference 22504419 10,768 0.284 0.108 8.70E−03
Child birth length 25281659 28,459 −0.133 0.089 1.34E−01
Child birth weight 23202124 26,836 −0.118 0.102 2.47E−01
Brain volume
Mean thalamus 25607358 13,193 −0.591 0.127 3.14E−06
Mean pallidum 25607358 13,142 −0.29 0.129 2.47E−02
ICV 25607358 11,373 0.347 0.133 9.00E−03
Mean accumbens 25607358 13,112 −0.29 0.158 6.64E−02
Mean putamen 25607358 13,145 −0.15 0.089 9.13E−02
Mean hippocampus 25607358 13,163 −0.204 0.132 1.20E−01
Mean caudate 25607358 13,171 0.012 0.105 9.06E−01
Neurological diseases
Alzheimer’s disease 24162737 54,162 0.181 0.11 9.87E−02
Parkinson’s disease 19915575 5691 −0.096 0.084 2.55E−01
Amyotrophic lateral sclerosis 27455348 36,052 −0.032 0.128 8.04E−01
White matter hyperintensities 25663218 17,940 0.100 0.094 2.87E−01
Personality traits
Neo-conscientiousness 21173776 17,375 −0.359 0.158 2.27E−02
Neo-openness to experience 21173776 17,375 0.088 0.118 4.56E−01
Neuroticism 27089181 170,911 −0.03 0.065 6.45E−01
Psychiatric traits
ADHD 20732625 5422 −0.276 0.152 6.90E−02
PGC cross-disorder analysis 23453885 61,220 −0.121 0.071 8.65E−02
Major depressive disorder 22472876 18,759 −0.165 0.102 1.05E−01
Schizophrenia 25056061 77,096 −0.067 0.044 1.30E−01
Subjective well-being 27089181 298,420 0.087 0.075 2.50E−01
ADHD (no GC) 27663945 17,666 −0.151 0.149 3.11E−01
Depressive symptoms 27089181 161,460 −0.038 0.071 5.93E−01
Autism spectrum disorder 0 10,263 0.041 0.092 6.53E−01
Anorexia nervosa 24514567 17,767 0.011 0.056 8.43E−01
Bipolar disorder 21926972 16,731 0.009 0.078 9.12E−01

rg: genetic correlation, SE: standard error, P: p-value