Table 1.
Table of CpG probes regulators of miRNA genes that were significantly differentially methylated in BCVY compared with BCO samples in the validation study using TCGA and the combined study data sets.
| Validated CpG probes | miRNA gene | TCGA | Combined study | ||
|---|---|---|---|---|---|
| % Methylation differences (BCVY - BCO) | p-value | % Methylation differences (BCVY - BCO) | p-value | ||
| cg04735310 | MIR196A1 | −11,13 | 4,13E-50 | −14,77 | 5,57E-04 |
| cg07234865 | MIR9-1 | −12,79 | 1,8E-45 | −14,30 | 6,72E-05 |
| cg08737296 | MIR124-3 | −13,29 | 7,3E-23 | −15,73 | 3,84E-03 |
| cg07792478 | MIR124-2 | −14,31 | 3,92E-21 | −10,07 | 1,03E-02 |
| cg05474726 | MIR124-2 | −11,78 | 2,66E-20 | −14,27 | 4,21E-03 |
| cg22333214 | MIR137 | −15,42 | 2,74E-20 | −11,66 | 1,41E-02 |
| cg04947764 | MIR184 | −10,56 | 5,67E-18 | −17,85 | 4,73E-04 |
| cg25147193 | MIR181C | −10,32 | 5,61E-17 | −13,96 | 8,03E-03 |
| cg16407471 | MIR129-2 | −10,07 | 5,6E-12 | −13,04 | 2,84E-02 |
| cg00210994 | MIR548G | −10,13 | 2,11E-07 | −14,67 | 2,29E-02 |
This table includes a list of 10 significant CpG probes and the corresponding miRNA that were regulated by them.