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. 2018 Sep 26;8:14420. doi: 10.1038/s41598-018-32831-2

Table 4.

Meta-analysis of studies reporting the prevalence of AB-positive animals.

No. prevalence inputs Sample size (No. animals) Weighted mean estimate Confidence Interval (95%) I2 (%)
Overall 334 459,095 49.20 (46.14–52.25) 99.76
Subgroup a
UN Region
Europe 152 343,629 48.38 (43.65–53.13) 99.86
North America 36 23,737 53.35 (41.94–64.60) 99.67
Central America 8 3,593 41.00 (24.60–58.48) 99.06
South America 27 17,743 53.43 (44.19–62.57) 99.27
East Asia 15 11,017 40.88 (28.86–53.46) 99.40
West Asia 37 11,257 51.06 (43.68–58.42) 98.35
South Asia 15 11,598 50.82 (37.35–64.22) 99.40
Australia 17 20,326 52.60 (43.01–62.09) 99.35
North Africa 8 1,942 53.97 (40.92–66.74) 96.12
Sub-Saharan Africa 19 14,253 42.06 (27.42–57.43) 99.69
Period
1961–1991 48 35,857 48.73 (41.20–56.28) 99.33
1992–2001 100 93,611 46.82 (41.38–52.29) 99.63
2002–2016 72 262,829 46.23 (39.12–53.41) 99.92
Not specified 114 66,798 53.38 (48.28–58.44) 99.40
Production system
Beef 40 63,210 45.14 (34.36–56.15) 99.87
Dairy 168 79,367 51.76 (47.67–55.84) 99.24
Mixed 42 96,219 48.52 (39.63–57.47) 99.86
Not specified 84 220,299 46.34 (40.64–52.09) 99.84
Age group
≤6 months 33 5,869 47.68 (37.17–58.29) 98.42
>6 months 64 176,293 49.05 (41.82–56.31) 99.86
Mixed 93 66,863 48.89 (43.01–54.78) 99.55
Not specified 144 210,070 49.81 (45.37–54.26) 99.75
Vaccination
Yes 21 28,653 66.04 (52.24–78.60) 99.80
No 177 272,973 45.19 (41.29–49.12) 99.74
Not specified 136 157,469 51.76 (46.89–56.60) 99.72
Clinical signs
Yes 93 32,828 52.26 (46.58–57.92) 99.03
No 25 15,077 36.85 (28.51–45.59) 99.08
Not specified 216 411,190 49.35 (45.48–53.21) 99.83
Programme
Yes 27 251,497 29.52 (20.58–39.31) 99.96
No 16 9,651 45.47 (35.69–55.43) 98.83
Not specified 291 197,947 51.34 (48.09–54.58) 99.51
Diagnostic method b
AB ELISA 171 352,277 45.67 (41.42–49.96) 99.84
NT 146 94,929 54.26 (49.90–58.58) 99.41
Mixed 7 2,562 38.38 (16.00–63.69) 99.32
Other 10 9,327 43.63 (23.04–65.42) 99.73

aAll p-values were ≤0.01 and were calculated using the Cochran’s Q-test.

bThe description of the diagnostic methods is provided in Table 1.