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. 2018 Sep 20;9:548. doi: 10.3389/fendo.2018.00548

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Copyright © 2018 Khalil, Cevik, Hung, Kolla, Roy and Suvorov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in liver gene expression in 10 months old mice are highly overlapping in groups exposed prenatally only and neonatally only to 1 mg/kg/body weight BDE-47: (A)–overlap in lists of significantly (FDR q ≤ 0.05) 2-fold differentially expressed genes; (B)–heat-map and unsupervised hierarchical clustering based on merged list 280 genes significantly (FDR q ≤ 0.05) 2-fold differentially expressed in pre- and/or postnatally exposed groups; (C)–changes in expression of non-overlapping genes (89 + 103 genes) in pre- and neonatal exposure groups, for majority of genes direction of change is the same in both groups.