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. 2018 Sep 20;9:548. doi: 10.3389/fendo.2018.00548

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Copyright © 2018 Khalil, Cevik, Hung, Kolla, Roy and Suvorov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GSEA enrichment of “KEGG Ribosome” gene set in mouse liver: (A)–mice were exposed prenatally to 1 mg/kg body weight BDE-47 and gene expression analyzed on PND300; (B)–mice were exposed perinatally to 0.2 mg/kg body weight BDE-47 and gene expression analyzed on PND140 (18). GSEA plot legend: 1-running enrichment score for the gene set; 2-vertical lines show where the members of the gene set appear in the ranked list of genes; 3 and 4-ranked list of differentially expressed genes from the most up-regulated (left of each plot) to the most downregulated (right of each plot). Regulation is shown in the heat-bar (3) and in the bar plot (4).