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. 2018 Sep 20;9:2170. doi: 10.3389/fimmu.2018.02170

Figure 1.

Figure 1

Anti-GITR combination therapy with anti-PD1 and XRT in 344SQ resistant tumors increases overall survival and promotes abscopal effects. Mice were inoculated on both right (primary) and left (secondary) legs with the second inoculation occurring 4 days after the first. (A) Anti-GITR therapy began on day 7 post inoculation and XRT began on day 8 post primary tumor inoculation with anti-PD1. (B) Plots of individual tumor growth values for primary tumors of various treatment arms (n = 8 per group), and (C) plots of survival by treatment group. *P ≤ 0.05 in Log-rank test.