FIG 14.

Coilin and PML protein are not recruited to VINORCs. 2089 cells or SNU-719 cells were left untreated (Ai to Aiv, Bix to Bxii, Cxvii to Cxx, and Dxxv to Dxxviii) or induced into the lytic phase of EBV infection by transfection with ZEBRA (Av to Aviii, Bxiii to Bxvi, Cxxi to Cxxiv, and Dxxix to Dxxxii). Cells were fixed then stained with primary antibodies specific for coilin (A and B; green), PML (C and D; green), RTA (A and C; red) and SON (B and D; red), and fluorophore-conjugated secondary antibodies. Transmitted light images are shown as indicated. Each row of two adjacent images depicts the same field of view. The reference bar in each image represents 10 μm.