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BICD2 binds to the HIV-1 capsid. (A) Capsid-like protein assemblies were titrated and incubated with 293T cell extracts. The reactions were then centrifuged, and the pelleted material was washed once and subjected to immunoblot analysis. Endogenous cellular BICD2 was probed for interaction with CA (A, CA tubes; B, CA-NC tubes).
