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Changes in abundance of RNA Pol mutations during passages
| Passage no. | Frequency of mutation (%)a |
||
|---|---|---|---|
| RPO147 M424I | RPO147 A1212V | RPO132 K1046Q | |
| 0 | ND | ND | ND |
| 2 | ND | ND | 1.7 |
| 4 | 3.0 | ND | 10.1 |
| 6 | 6.1 | ND | 17.6 |
| 8 | 11.2 | 1.2 | 38.1 |
| 9 | 16.8 | 1.5 | 50.1 |
| 10 | 24.2 | 1.9 | 55.3 |
ND, not detected.
