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. 2018 Sep 26;92(20):e01261-18. doi: 10.1128/JVI.01261-18

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FIG 3 — Protein association networks. The online tool STRING was used to create protein functional association networks of upregulated (A and B) and downregulated (C to E) genes with a >1.5-fold modulation of expression (P < 0.05). (A) Genes from GO categories related to cell cycle regulation were combined to create the network. (B) Genes from GO categories related to DNA metabolism were combined to create the network. (C) Genes from GO categories related to skin development and differentiation were combined to create the network. (D) Genes from GO categories related to inflammation and the immune response were combined to create the network. (E) Genes from GO categories related to apoptosis and cell death were combined to create the network. Thicker and darker lines represent greater confidence in the protein interaction on the basis of the supporting data. Genes that had no connection to any other gene within the network were excluded from the diagram.