FIG 5.

Effect of the proteasome inhibitor MG132 on BoHV-1 infectivity. MDBK cells were treated at the indicated concentrations for 20 min at 37°C. Cells were infected with BoHV-1 v4a (MOI of 2) for 6 h in the continued presence of the agent. The beta-galactosidase expression was calculated as a percentage of activity in untreated, infected cells. Cytotoxicity is shown as percent LDH activity. Values are the means from quadruplicate samples with standard deviations. Results are representative of at least three independent experiments.