Figure 4. Treatment with BDB suppresses both M1 and M2 macrophage recruitment in hearts of mice after MI. (A) Gating strategy for CD11b⁺CD45⁺Ly6G⁻F4/80⁺CD206⁺ and CD11b⁺CD45⁺Ly6G⁻F4/80⁺CD206⁻ macrophages in hearts from BDB-treated mice after MI. (B-D) Effect of BDB treatment on the recruitment of (B) total macrophages, (C) M1, and (D) M2 macrophages in injured hearts from vehicle or BDB-treated mice on day 3 and 7 after MI. Data are expressed as mean±SEM (n=6–8).

BDB = 3-Bromo-4,5-dihydroxybenzaldehyde; MI = myocardial infarction.

^*The p<0.05 compared with vehicle group.