Figure 5. Administration of BDB reduced the levels of inflammatory cytokines in infarcted hearts. (A-D) Hearts from 3 days MI mice treated with vehicle and BDB (100 mg/kg) were evaluated for protein expressions by ELISA analysis; (A) TNF-α, (B) MCP-1, (C) IL-1β, and (D) IL-6. (E-H) Hearts from 7 days MI mice treated with vehicle and BDB (100 mg/kg) were evaluated for protein expressions by ELISA analysis: (E) TNF-α, (F) MCP-1, (G) IL-1β, and (H) IL-6. Data are expressed as mean±SEM (n=6–8).

BDB = 3-Bromo-4,5-dihydroxybenzaldehyde; ELISA = enzyme-linked immunosorbent assay; IL = interleukin; MCP = monocyte chemoattractant protein; MI = myocardial infarction; TNF = tumor necrosis factor; SEM = standard error of measurement.

^*The p<0.05 compared with vehicle group.