Table 1.
Changes in complete blood count, procalcitonin, serum biochemistry, and blood coagulation profiles
| Age (mo) (1in-patient admission; 2discharge to out-patient follow-up) | 5.1 | 5.61 | 6 | 6.2 | 6.5 | 6.8 | 7 | 7.22 | 9.5 | |
| Complete blood count (reference range) | White blood cell (4-10 × 109/L) | 16.9 | 21.1 | 71.7 | 26.4 | 33.7 | 45.8 | 30.3 | 24.3 | 14.3 |
| Neutrophil (20%-50%) | 58.1 | 39.8 | 58.0 | 63.1 | 62.0 | 63.0 | 62.7 | 64.4 | 38.9 | |
| Lymphocyte (45%-75%) | 36.2 | 53.1 | 31.1 | 28.7 | 28.9 | 15.0 | 29.5 | 27.8 | 51.4 | |
| Abnormal lymphocytes (0%) | NA | 0.0 | 0.0 | NA | 0.0 | 17.0 | 0.0 | 0.0 | NA | |
| Platelet count (100-300 × 109/L) | 764.0 | 513.0 | 993.0 | 464 | 387.0 | 494.0 | 279.0 | 397 | 386.0 | |
| Hemoglobin (110-160 g/L) | 78.0 | 85.2 | 78.2 | 60.1 | 64.0 | 65.2 | 90.0 | 88.0 | 122.0 | |
| Red blood cell count (4.0-5.5 × 1012 /L) | 3.5 | 3.1 | 2.8 | 2.0 | 2.0 | 2.2 | 2.9 | 2.9 | 4.3 | |
| Reticulocyte (0.5%-1.5%) | NA | 2.9 | 6.7 | NA | 6.3 | 7.8 | 3.3 | 6.8 | 1.0 | |
| C-reactive protein (< 8 mg/L) | 1.0 | 8.0 | 90.0 | 32.0 | 43.0 | 37.0 | 45.0 | 8.0 | 8.0 | |
| Procalcitonin (< 0.05 ng/mL) | NA | 4.6 | 17.4 | 7.7 | 13.4 | NA | NA | NA | NA | |
| Serum biochemistry (reference range) | Albumin (35-55 g/L) | 29.0 | 34.6 | 27.3 | 30.8 | 32.3 | 28.7 | 38.5 | 39.1 | 43.0 |
| Alanine aminotransferase (0-40 IU/L) | 41.0 | 45.0 | 17.0 | 13.0 | 4.0 | 50.0 | 49.0 | 38.0 | 29.0 | |
| Aspartate aminotransferase (0-40 IU/L) | 100.0 | 104.0 | 46.0 | 37.0 | 66.0 | 98.0 | 70.0 | 62.0 | 41.0 | |
| Total bilirubin (5.1-17.1 μmol/L) | 68.0 | 120.4 | 133.0 | 132.9 | 126.8 | 110.6 | 90.1 | 42.9 | 8.1 | |
| Direct bilirubin (0-6 μmol/L) | 53.0 | 76.9 | 93.7 | 96.1 | 86.6 | 70.4 | 61.8 | 29.8 | 4.4 | |
| γ-glutamyl transferase (7-50 IU/L) | 73.0 | 61.0 | 76.0 | 58.0 | 54.0 | 57.0 | 107.0 | 230.0 | 122.0 | |
| Total bile acid (0-10 μmol/L) | NA | 182.8 | 123.3 | 152.4 | 137.2 | 157.4 | 311.7 | 282.3 | 34.6 | |
| Alkaline phosphatase (42-383 IU/L) | 307.0 | 137.0 | 149.0 | 119.0 | 122.0 | 148.0 | 178.0 | 214.0 | 378.0 | |
| Blood glucose (3.9-5.8 mmol/L) | NA | 1.2 | 1.6 | 8.4 | 1.1 | NA | NA | 3.6 | NA | |
| Lactic acid (0-2 mmol/L) | NA | 3.9 | NA | 3.6 | 3.6 | NA | NA | NA | NA | |
| Ammonia (10-47 μmol/L) | NA | 88.0 | NA | NA | NA | NA | NA | 55.0 | NA | |
| Total cholesterol (3.1-5.2 mmol/L) | 3.1 | 2.0 | NA | 2.3 | 2.5 | NA | 2.8 | 4.4 | 3.1 | |
| LDL-cholesterol (1.30-3.90 mmol/L) | NA | NA | NA | 1.0 | NA | NA | NA | NA | NA | |
| HDL-cholesterol (0.91-2.05 mmol/L) | NA | NA | NA | 0.3 | NA | NA | NA | NA | NA | |
| Triglyceride (0.56-1.70 mmol/L) | NA | 2.0 | NA | 2.7 | 2.1 | NA | 2.1 | 1.8 | 1.5 | |
| Blood coagulation profiles (reference range) | Activated partial thromboplastin time (28.0-44.5 s) | NA | 48.1 | NA | 57.5 | 56.4 | 53.9 | 47.7 | 42.3 | 43.8 |
| D-dimer (0-0.3 mg/L) | NA | 0.94 | NA | 2.06 | 1.15 | 0.97 | 0.7 | 0.51 | NA | |
| Fibrinogen (2-4 g/L) | NA | 1.45 | NA | 1.82 | 2.29 | 2.54 | 3.03 | 3.46 | 3.44 | |
| Fibrinogen degradation products (0-5 μg/ML) | NA | 1.31 | NA | 5.22 | 2.35 | 2.78 | 1.47 | 1.16 | NA | |
| Thrombin time (14-21 s) | NA | 20.4 | NA | 19.1 | 19.9 | 19.9 | 15.8 | 18.4 | 15.2 | |
| International normalized ratio (0.8-1.2) | NA | NA | NA | 1.29 | 1.26 | 1.35 | 1.3 | 1.03 | 0.99 | |
| Prothrombin time (12.0-14.8 s) | NA | NA | NA | 16 | 15.7 | 16.5 | 16.1 | 13.5 | 13.1 | |
| Prothrombin time activity (80%-100%) | NA | NA | NA | 67 | 69 | 63 | 66 | 95 | 103 | |
NA: Not available.