Fig. 1.

Examples of isolated islet preparations. (a) An example of a crude feline islet preparation stained with dithizone (red hue) to differentiate endocrine tissue (islets) from exocrine tissue. The significant variation in size and shape of the red-stained islets can be clearly seen in the image, along with variation in the intensity of the dithizone stain. (b) An example of a canine islet prep stained with dithizone. By comparison the islets are larger in size, but also non-uniformly shaped or stained. (c) Dithizone-stained human islets viewed through a microscope binocular with a grid used to categorize islet sizes into bins for IEQ calculations.

IEQ: islet equivalency.