Table 2.
Transplant group | Outcome | Cells/mouse | IEQ/mouse |
---|---|---|---|
1 | 100% partial response | 5.00 M | 2500 |
2 | 33% failure | 5.13 M | 3500 |
33% partial response | |||
33% normal glycemia | |||
3 | 100% normal glycemia | 6.17 M | 2500 |
4 | 100% normal glycemia | 7.25 M | 4000 |
Transplants on the left side of the table show the volume of islets transplanted into the mice based on IEQ. When calculated as IEQ, some of the mice in each group responded fully to the transplant with normal glycemia. However, when the same transplants were calculated based on cell numbers (right side of table), the results suggest that transplants with 6.17 million cells or more were successful 100% of the time. N = 10 mice.
IEQ: islet equivalency.