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. 2018 Jun 28;27(7):1017–1026. doi: 10.1177/0963689718779898

Table 2.

Results from studies transplanting canine islets into diabetic NOD-SCID mice.

Transplant group Outcome Cells/mouse IEQ/mouse
1 100% partial response 5.00 M 2500
2 33% failure 5.13 M 3500
33% partial response
33% normal glycemia
3 100% normal glycemia 6.17 M 2500
4 100% normal glycemia 7.25 M 4000

Transplants on the left side of the table show the volume of islets transplanted into the mice based on IEQ. When calculated as IEQ, some of the mice in each group responded fully to the transplant with normal glycemia. However, when the same transplants were calculated based on cell numbers (right side of table), the results suggest that transplants with 6.17 million cells or more were successful 100% of the time. N = 10 mice.

IEQ: islet equivalency.