Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 18;27(7):1140–1153. doi: 10.1177/0963689718779766

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 5. — Expression of inflammatory and anti-inflammatory markers. (a) The densities of inflammatory and anti-inflammatory markers. (b) Quantitative data obtained by densitometry showing optical densities (OD) relative to GFP-MSCs. The expression of TNF-α and IL-6 was significantly lower in combination and HO-1-MSCs groups compared to BDNF and GFP-MSCs groups (*P ≤ 0.05). The expression of COX2 was significantly decreased in all combination, BDNF-, and HO-1-MSCs groups compared to the GFP-MSCs group (*P ≤ 0.05). pSTAT3 was upregulated in both combination and HO-1-MSCs group compared to BDNF- and GFP-MSCs groups (*P ≤ 0.05); its expression was also higher in the BDNF group compared to the GFP-MSCs group (^#P ≤ 0.05). IL-10 was significantly higher in the combination and HO-1 groups (*P ≤ 0.05) compared to the BDNF and GFP-MSCs groups. The graph represents mean ± standard error of four dogs per groups, as determined by densitometry relative to β-actin.