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. 2018 Jul 10;45(4):239–250. doi: 10.1159/000490714

Table 3.

Genotyping results for ISBT 005 (Lutheran) to ISBT 013 (Scianna) and for ISBT 014 (Dombrock) to ISBT 034 (Vel)a

Blood group system
Lutheran Lutheran Lutheran Kell Kell Kell Kell Diego Wright Cartwright Scianna Dombrock Dombrock Dombrock Colton Landst.-Wiener Cromer Cromer Cromer Knops Knops Knops Indian Vel
ISBT number 005 005 005 006 006 006 006 010 010 011 013 014 014 014 015 016 021 021 021 022 022 022 023 034

Frequent Lub Lu8 Aub k Kpb K11 Jsb Dib Wrb Yta SC:1 Dob Hy+ Jo(a+) Coa LWa Cra Tca Kna McCa Vil- Inb Vel+
antigen

Rare antigen Lua Lu14 Aua K Kpa K17 Jsa Dia Wra Ytb SC:2 Doa Hy- Jo(a-) Cob LWb Cra- Tcb Tcc Knb McCb Vil+ Ina Vel-

Geneva
AA 1,237 1,304 623 1,212 1,313 1,313 1,313 1,318 1,294 1,163 1,319 507 1,323 1,318 1,239 1,318 1,302 1,318 1,268 1,311 1,296 1,307 1,297
Aa 78 16 575 106 16 6 6 3 3 151 12 623 2 3 80 3 1 1 2 53 8 29 0 33
aa 1 0 132 1 1 0 0 0 0 7 0 201 0 0 1 0 0 0 0 0 2 6 0 1
invalid 32 28 18 29 18 29 29 27 51 27 17 17 23 27 28 27 45 27 27 27 17 41 17

Lausanne
AA 1,397 1,451 721 1,392 1,478 1,487 1,486 1,493 1,502 1,324 1,495 533 1,510 1,478 1,390 1,491 1,407 1,489 1,421 1,471 1,487 1,490 1,459
Aa 83 40 649 101 32 6 6 0 0 162 15 735 1 2 100 2 2 0 3 70 8 21 2 52
aa 1 0 138 0 1 0 0 0 0 5 0 242 0 0 3 0 0 0 0 1 0 3 0 0
invalid 45 35 18 33 15 33 34 33 24 35 16 16 15 46 33 33 117 34 34 47 15 34 15

Neuchâtel
AA 957 1,002 502 957 1,002 1,026 1,026 1,028 999 909 1,020 361 1,028 1,027 956 1,024 1,027 1,026 972 1,024 1,018 1,023 1,002
Aa 69 25 416 69 27 2 2 0 0 116 8 499 1 0 68 4 0 0 1 55 4 10 1 27
aa 0 105 2 0 0 0 0 0 1 0 162 0 0 4 0 0 0 0 1 0 1 0 0
invalid 3 1 6 1 0 1 1 1 30 3 1 7 0 2 1 1 2 2 1 1 0 5 0

Sion
AA 685 732 376 692 742 745 744 746 755 659 748 275 755 742 699 741 716 744 723 742 752 746 755
Aa 53 13 313 50 13 1 2 0 0 85 7 375 0 0 46 5 0 0 1 23 0 3 0 0
aa 1 1 66 2 0 0 0 0 0 2 0 104 0 0 1 0 0 0 0 0 0 0 0 0
invalid 21 14 5 16 5 14 14 14 5 14 5 6 5 18 14 14 44 15 14 18 5 14 5

Basel
AA 982 1,057 516 997 1,033 1,064 1,060 1,080 1,027 955 482 379 1,047 1,064 1,004 1,073 1,007 1,073 1,024 1,063 1,047 1,079 475
Aa 82 22 426 69 18 3 1 0 0 122 1 522 0 0 75 7 0 0 4 56 2 9 0 9
aa 0 0 100 3 0 0 0 0 0 3 0 154 0 0 1 0 0 0 0 0 0 0 0 0
invalid 158 143 180 153 171 155 161 142 195 142 739 167 175 158 142 142 215 145 142 157 166 143 738

Aarau
AA 790 841 411 781 833 844 844 849 854 758 854 288 855 850 776 843 850 849 792 849 854 846 817
Aa 60 9 368 68 22 6 6 1 1 91 1 417 0 0 69 7 0 0 1 57 1 1 0 38
aa 0 0 76 1 0 0 0 0 0 2 0 150 0 0 2 0 0 0 0 1 0 0 0 0
invalid 5 5 0 5 0 5 5 5 0 4 0 0 0 5 8 5 5 5 5 5 0 9 0

Luzern
AA 2,514 2,661 1,333 2,495 2,664 2,697 2,712 2,716 2,710 2,446 898 975 2,724 2,719 2,494 2,701 2,715 2,717 2,535 2,719 2,728 2,708 876
Aa 197 58 1,147 222 72 24 8 1 2 261 4 1,306 4 1 219 19 0 0 0 184 1 8 1 26
aa 6 0 252 4 1 0 0 0 0 12 0 456 0 0 3 0 0 0 0 1 0 0 0 0
invalid 53 51 38 49 33 49 50 53 58 51 1,868 33 42 50 54 50 55 53 50 50 34 61 1,868

Zurich
AA 22,013 23,287 11,766 21,953 23,237 23,628 23,591 23,698 23,120 21,075 14,681 8,451 23,717 23,713 21,971 23,536 23,630 23,677 22,459 23,684 23,680 23,702 14,753
Aa 1,678 440 9,773 1,693 527 66 74 36 9 2,567 98 11,427 7 13 1,705 201 14 4 44 1,259 36 115 3 26
aa 29 5 2,207 50 4 0 0 1 0 92 0 3,911 0 0 31 1 0 0 0 18 2 6 0 3
invalid 338 326 312 362 290 364 393 323 929 324 9279 269 334 332 351 320 414 333 322 336 257 353 9,276

Lugano
AA 718 745 322 698 749 758 754 753 728 674 380 269 762 760 691 757 753 756 726 759 759 758 382
Aa 43 12 335 56 12 0 1 0 1 80 3 382 0 0 61 4 0 0 0 35 1 4 0 0
aa 0 0 105 4 0 0 0 0 0 6 0 112 0 0 2 0 0 0 0 0 0 0 0 1
invalid 7 11 6 10 7 10 13 15 39 8 385 5 6 8 14 7 15 12 7 8 5 10 385

St. Gallen
AA 1,361 1,435 745 1,349 1,444 1,460 1,453 1,460 1,435 1,297 1,458 491 1,447 1,462 1,347 1,450 1,461 1,460 1,395 1,462 1,458 1,454 1,404
Aa 99 27 596 113 22 1 8 1 0 158 7 724 0 0 113 12 1 0 1 65 0 7 0 60
aa 2 0 124 0 0 0 0 0 0 6 0 249 0 0 2 0 0 0 0 1 0 0 0 0
invalid 14 14 11 14 10 15 15 15 41 15 11 12 29 14 14 14 14 15 15 14 11 22 12

Chur
AA 1,343 1,398 636 1,301 1,396 1,411 1,419 1,422 1,421 1,249 393 516 1,426 1,422 1,318 1,415 1,420 1,417 1,360 1,421 1,421 1,421 395
Aa 76 24 628 119 33 12 3 0 0 166 2 665 3 0 100 7 1 2 1 60 0 9 0 0
aa 2 0 161 1 0 0 0 0 0 7 0 247 0 0 2 0 0 0 0 2 0 0 0 0
invalid 20 19 16 20 12 18 19 19 20 19 1,046 13 12 19 21 19 20 21 19 20 11 20 1,046

Total
AA 33,997 35,913 17,951 33,827 35,891 36,433 36,402 36,563 35,845 32,509 23,728 13,045 36,594 36,555 33,885 36,349 36,288 36,526 34,675 36,505 36,500 36,534 23,615
Aa 2,518 686 15,226 2,666 794 127 117 42 16 3,959 158 17,675 18 19 2,636 271 19 7 58 1,917 61 216 7 271
aa 42 7 3466 68 7 0 0 1 0 143 0 5988 0 0 52 1 0 0 0 25 4 16 0 5
invalid 696 647 610 692 561 693 734 647 1,392 642 13,367 545 641 679 680 632 946 662 636 683 521 712 13,362

% Invalid 1.87 1.74 1.64% 1.86 1.51 1.86 1.97 1.74% 3.74 1.72 n.a. 1.46 1.72 1.82 1.83 1.70 2.54 1.78 1.71 1.83 1.4% 1.9% n.a.

Overall 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253 37,253
a

Top to bottom: Numbers of frequent homo- (AA), hetero- (Aa), and rare homozygotes(aa) and invalid typings for each BTS, identified by their respective head quarter locations, ordered according to geographical latitude from West to East. Left to right: antigens tested, ordered according to the ISBT number of the respective blood group system. Donors with rare blood group phenotypes are underlayed in gray (excluding blood group system Knops) and are summing up to a total of 326 (line ‘rare homo’ of total numbers). Only 23,886 and 23,848 blood donors, were analyzed for Scianna rs56025238 and Vel rs566629828, respectively. Donor samples not tested for these antigens are indicated as n.t.