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. 2018 Jul 25;46(17):9189–9200. doi: 10.1093/nar/gky670

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — CEMOVIS of interphase nuclei of the human cell lines KE37 (A, B and D) and HT29 (C and E). (A) Local view of a nucleus limited by the NE. An NPC is visible. (B) A chromatin-dense region (*), delineated by the white dotted line, coexists with a less dense region. (B and C) Striations are visible, either locally (black arrows) or extending over longer distances (white arrows). (D and E) Nucleosomes visualized in side views. The patterns are compared with CTF-modulated projections of the crystallographic structure of the particle (from PDB ID: 1 EQZ). (D’ and E’) The distance between the DNA gyres P, is measured on line profiles indicated in yellow in (D) and (E). (F) Distribution of P for the two cell types.