Effects of ascorbic acid on MnSOD and CuZnSOD levels in the carotid body and adrenal medulla from CIH-rats. Western blot assays performed on CB homogenates (A), demonstrate that ascorbic acid prevented the CIH-induced increase in MnSOD levels in rat CB (B), while CuZnSOD did not change either with CIH or the CIH-AA exposure (C) *p<0.05 versus sham group, Bonferroni after one-way ANOVA n=11 rats per group. Western blot realized with adrenal medulla homogenates (D) from sham, CIH or CIH-AA rats did not show statistical differences in MnSOD (E) or CuZnSOD levels (F). One-way ANOVA, n=4–5 rats per group. Abbreviations: CIH, chronic intermittent hypoxia; CB, carotid body.