Table 2.
Wilcoxon matched-pairs test within each group
| Control | PTx3 | PTx10 | PTx10 + minocycline | Inactivation | PTx10 + tsDCs | |
|---|---|---|---|---|---|---|
| No. of IZ ChAT+ INs | W = 5.00, p = 0.3125 | W = 5.00, p = 0.5 | W = 0.00, p = 0.0039** | W = 3.00, p = 0.5 | W = 0.00, p = 0.0313* | W = 3.00, p = 0.1563 |
| C bouton density | W = −2.00, p = 0.0938 | W = 0.00, p = 0.0625 | W = 0.00, p = 0.0313* | W = 5.00, p = 0.5 | W = 0.00, p = 0.0313* | W = −7.00, p = 0.5 |
| No. of IZ NeuN+ neurons | W = −0.00, p = 0.1346 | W = 1.5, p = 0.0488* | ||||
| No. of motoneurons | W = 18.00, p = 0.5 | |||||
| No. of PV+ INs | W = −2.00, p = 0.375 | |||||
| Mann–Whitney U test within each group | ||||||
| No. of CD68+ microglia | U = 17.5, p = 0.5 | U = 32, p = 0.4789 | U = 3.0, p = 0.005** | U = 17.0, p = 0.4676 | U = 6.5, p = 0.0003*** | |
| Intensity of microglial CD68 clusters | U = 168.0, p = 009545 | U = 123.0,p = 0.2397 | U = 124.0, p = 0.0229* | U = 202.0, p = 0.2443 | ||
| Intensity of engulfed ChAT | U = 164.0, p = 0.3252 | U = 159.0, p = 0.203 | U = 228.0, p = 0.0426* | U = 245.0, p = 0.1029 | U = 295.0, p = 0.003** | |
| Unpaired t test within each group | ||||||
| Intensity of microglial C1q | t(50) = 0.56, p = 0.5725 | t(43) = 0.45, p = 0.6499 | t(112) = 2.246, p = 0.0266* | t(89) = 0.66, p = 0.5111 | t(88) = 0.65, p = 0.5147 |
*p < 0.05;
**p < 0.01;
***p < 0.001.