Figure 2.

Solution structure of TERRA RNA GQ. (A) Dimer is composed of four symmetric rGGGUUAGGGU strands (chains)—blue, red, green and black, respectively, guanines of quartets are gray; (B) structure of bimolecular 2M18 GQ containing two propeller loops; (C) single strand of 2M18 (PH) with nucleobases of the UUA propeller loop in blue; (D) detailed view of the propeller loop conformation with numbering of nucleotides. Note that terminal (flanking) uracils were removed from all simulated structures.