Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
SNM1A has hairpin-opening endonuclease activity. (A) Vectors for hairpin-opening assay in yeast. (B) Analysis of SNM1A endonuclease activity in pso2Δ yeast. Reversion frequency was normalized to PSO2 complemented yeast. Assays were performed in quadruplicate where error bars show the standard deviation for all assays. Pso2 expression was below detection by monoclonal anti-polyHis antibody (Sigma: H1029). ** denotes a P-value <0.01 compared to empty vector using one-tail t-test.
