Table 1.
Physical and biochemical parameters of experimental rats.
| NC | DKD | DKD+TP | |
|---|---|---|---|
| BW(g) | 512.7 ± 58.3 | 326.8 ± 41.6* | 350.1 ± 34.9* |
| FPG (mmol/L) | 6.9 ± 0.7 | 27.2 ± 3.3* | 25.4 ± 4.2* |
| KW/BW(mg/g) | 3.02 ± 0.21 | 5.85 ± 0.49* | 4.77 ± 0.42*# |
| UMA (μg/24 h) | 26.5 ± 9.2 | 243.6 ± 35.1* | 159.0 ± 29.3*# |
| TG (mmol/L) | 1.6 ± 0.9 | 4.1 ± 1.7* | 3.9 ± 2.2* |
| TC (mmol/L) | 2.8 ± 1.3 | 6.2 ±2.3* | 6.4 ± 2.5* |
| ALT (U/L) | 46.5 ± 8.6 | 53.4 ± 6.7 | 49.4 ± 10.9 |
| AST (U/L) | 75.6 ± 19.7 | 86.1 ± 15.4 | 89.2 ± 14.8 |
| BUN (mmol/L) | 7.9 ± 2.7 | 8.4 ± 2.1 | 8.0 ± 1.8 |
| Scr (μmol/L) | 35.3 ± 4.2 | 37.8 ± 4.6 | 38.1 ± 4.9 |
n=15 per group. Data are expressed as the mean ± SD. BW, body weight; FPG, fasting plasma glucose; KW/BW, kidney weight to body weight ratio; UMA, urinary microablumin; TG, triglyceride; TC, total cholesterol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; and Scr, serum creatinine; *P < 0.05 vs. the NC group, #P < 0.05 vs. the DKD group. NC: normal control; DKD: diabetic kidney disease; TP: triptolide.