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Polydatin attenuates hepatic steatosis and apoptosis induced by LPS and PA. HepG2 cells were induced by the combination of 1 μg/ml LPS and 0.25 mM PA and treated with or without polydatin for 24 h. (A) Oil red O staining in HepG2 cells. (B) The contents of triglyceride in HepG2 cells. (C) Apoptotic cells were measured by means of TUNEL assay. (D) The proportion of LDH release from HepG2 cells. ###p < 0.001, ####p < 0.0001 vs Control. *p < 0.05, ****p < 0.0001 vs HepG2 induced by PA.
