Fig. 1.

(A). Diagram of the autoregressive cross-lagged model of MAS-XR treatment vs. placebo on ADHD improvement and cocaine abstinence within the first 6 weeks of the trial (n = 126). Autoregressive effects are represented as horizontal arrows; cross-lagged effects are illustrated by diagonal arrows between abstinence and ADHD improvement. (B). Paths achieving statistical significance based on the autoregressive cross-lagged model. Corresponding model estimated odds ratios (OR) and 95% confidence intervals (CI) are presented in Table 1.