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. 2018 Sep 27;15:283. doi: 10.1186/s12974-018-1318-y

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© The Author(s). 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The individual data on the pre- and postoperative levels of serum and cerebrospinal fluid (CSF) levels of interleukin-8 (IL-8). The increase in serum levels of IL-8 seen after surgery was clearly attenuated by methylprednisolone (steroid), while methylprednisolone induced a pronounced accentuation of the CSF IL-8 response to cardiac surgery