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. 2018 Sep 26;18:928. doi: 10.1186/s12885-018-4824-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — I₂ treatment significantly reduces OCT-4, SOX2, KLF4 and NANOG in SiHa cells grown as spheres. Monolayer cultures of SiHa cells were treated with 200 μM (I₂) for 24 h (tinted with line), without treatment (black line), isotype (long dashes) (a, d, g, j). Sphere cultures of SiHa cells were treated with 200 μM (I₂) for 24 h (tinted with line), without treatment (black line), isotype (long dashes) (b, e, h, k). Markers were analyzed by flow cytometry (a, b, d, e, g, h, j, k). Data are expressed as mean ± SD (n = 3 independent assays), and the asterisk indicates a significant difference with respect to the control (*P < 0.05, ***P < 0.001) (c, f, i, l)