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. 2018 Sep 26;38:60. doi: 10.1186/s40880-018-0329-5

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Application of MiniPDX assay in clinical setting. Representative clinical case study of MiniPDX assay in patient MDX245, with bilateral multiple pulmonary metastases from low grade endometrial stromal sarcoma. a Response of MDX245 patient’s MiniPDX model to single agent apatinib and combined apatinib with olapanib. (n = 6; *, P < 0.05 in comparison to the vehicle group); b, c Chest CT scans of patient MDX245, before and 4 months after treatment. Note a significant eradiation in bilateral multiple masses including a massive one (dotted oval). Ola olapanib, Apa apatinib, Pazo pazopanib