Table 3.
RCTs of FMT in UC.
| Costello et al [41]. | Moayyedi et al [14]. | Paramsothy et al [15]. | Rossen et al [16]. | |
|---|---|---|---|---|
| Number | 73(38 FMT/35 placebo) | 75(38 FMT/37 placebo) | 81(41 FMT/40 placebo) | 48(23 FMT/25 placebo) |
| Severity | mild-moderate | mild-moderate | mild-moderate | mild-moderate |
| Route | colonoscopy and enema | enema | colonoscopy and enema | nasoduodenal |
| Placebo | Autologous stool | water | water | Autologous stool |
| Donor | unrelated | unrelated | unrelated | unrelated |
| Fresh vs Frozen | Frozen | frozen and fresh | Frozen | Fresh |
| Frequency | 3 | 6 | 40(5x/week for 8 weeks) | 2 |
| Follow-up | 8 weeks | 6 weeks | 8 weeks | 12 weeks |
| Remission | 12/38(FMT) | 9/38(FMT) | 11/41(FMT) | 7/23(FMT) |
| FMT/placebo | 3/35(placebo) | 2/37(placebo) | 3/40(placebo) | 5/25(placebo) |
| Response | 21/38(FMT) | 15/38(FMT) | 22/41(FMT) | 11/23(FMT) |
| FMT/placebo | 7/35(placebo) | 9/37(placebo) | 9/40(placebo) | 13/25(placebo) |