Table 2.
Comparison of studies on the treatment of CNV secondary to PIC.
| Coco et al. [15] | Peng et al. [12] | Fong et al. [6] | Menezo et al. [11] | Zhang et al. [8] | Our study | |
|---|---|---|---|---|---|---|
| Study design | Retrospective | Prospective | Prospective | Retrospective | Prospective | Retrospective |
| No. of eyes | 8 | 16 | 5 | 10 | 12 | 24 |
| Treatment | vPDT | Conbercept | vPDT+ Corticosteroid | Ranibizumab | Bevacizumab | Ranibizumab +/- Corticosteroid |
| Initial BCVA (logMAR) | 0.42 | 0.70 | 0.54 | 0.72 | 0.49 | Ranibizumab: 0.68; Ranibizumab+ Corticosteroid: 0.82 |
| Final BCVA (logMAR) | 0.51 | 0.44 | 0.39 | 0.37 | 0.23 | Ranibizumab: 0.34; Ranibizumab+ Corticosteroid: 0.22 |
| Mean follow-up (months) | 22.7 | 6 | 12 | 12.5 | 12 | Ranibizumab: 23.3; Ranibizumab+ Corticosteroid: 24.5 |
| Improved or stable BCVA (eyes) | 5 (62.5%) | 16 (100%) | 4 (80%) | 9 (90%) | 12 (100%) | Ranibizumab: 13 (92.9%); Ranibizumab+ Corticosteroid: 10 (100%) |
Improved or stable BCVA means that BCVA of the patient kept stable (less than 0.1 in change) or was improved to more than 0.1 after the treatment.