Table 2: Measurement of the Anticoagulant Effects of Direct Oral Anticoagulants using Specific and Non-specific Assays.

Test		Dabigatran	Rivaroxaban	Apixaban
Specific assay	Drug specific	Hemoclot and ecarin clotting-time	Anti-Xa	Anti-Xa
Non-specific assays	aPTT PT TT	↑↑↑ ↑ ↑↑↑↑	↑ ↑↑ No effect	↑ ↑↑ No effect

Based on Huisman et al., 2015[54] and Cuker et al., 2014.[55]