Table 4.
Gene set enrichment test involving the genes within 2 Mb of the SNP with P < 0.0004
| Process (GO term) | Number of genes in process | P value |
|---|---|---|
| Ubiquitin-protein transferase activity | 11 | 0.002 |
| Intercalated disc | 4 | 0.011 |
| MHC class II protein complex | 3 | 0.013 |
| Negative regulation of axon extension involved in axon guidance | 4 | 0.019 |
| Mitophagy in response to mitochondrial depolarization | 7 | 0.019 |
| Palate development | 6 | 0.022 |
| Regulation of membrane potential | 5 | 0.023 |
| Chloride channel activity | 4 | 0.024 |
| Oxalate transmembrane transporter activity | 3 | 0.035 |
| Secondary active sulfate transmembrane transporter activity | 3 | 0.035 |
| Sulfate transmembrane transporter activity | 3 | 0.035 |
| Connexon complex | 3 | 0.035 |
| Intermediate filament organization | 3 | 0.042 |
| Keratinocyte differentiation | 4 | 0.043 |
| Endoplasmic reticulum membrane | 11 | 0.049 |
| Bicarbonate transmembrane transporter activity | 3 | 0.049 |
| Complement activation | 3 | 0.049 |