Table 2. Mutation rates of BPSs.
Mutation rate (× 10–9 per nucleotide per generation) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Mutation type* | WT | ΔendoMS | dnaE(D647G) | ΔendoMS-dnaE (D647G) | ||||||
Transition | A:T→G:C | A→G | 0.84 | 0.53 | 52 | 44 | 37 | 26 | 430 | 460 |
T→C | 0.22 | 37 | 17 | 520 | ||||||
G:C→A:T | G→A | 0.57 | 0.80 | 33 | 47 | 24 | 39 | 360 | 330 | |
C→T | 1.04 | 62 | 56 | 310 | ||||||
Transversion | A:T→C:G | A→C | 0.19 | 0.24 | 0.38 | 0.57 | 17 | 16 | 16 | 14 |
T→G | 0.28 | 0.75 | 15 | 14 | ||||||
G:C→T:A | G→T | 0.16 | 0.20 | - | 0.16 | 11 | 14 | 11 | 14 | |
C→A | 0.25 | 0.20 | 17 | 21 | ||||||
A:T→T:A | A→T | 0.04 | 0.06 | - | <0.19 | 4.7 | 3.5 | 6.0 | 6.3 | |
T→A | 0.09 | - | 2.3 | 8.5 | ||||||
G:C→C:G | G→C | 0.07 | 0.08 | - | <0.16 | 0.39 | 1.0 | 6.0 | 4.5 | |
C→G | 0.09 | - | 1.7 | 4.1 | ||||||
Indels | Deletion | 0.06 | <0.07 | 4.9 | 5.6 | |||||
Insertion | 0.04 | <0.07 | 7.1 | 7.3 | ||||||
Overall | 1.1 | 46 | 62 | 420 |
*Mutations are represented as that occurred in leading strand.