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. 2018 Jun 6;46(12):6152–6165. doi: 10.1093/nar/gky481

Table 2. Mutation rates of BPSs.

Mutation rate (× 10–9 per nucleotide per generation)
Mutation type* WT ΔendoMS dnaE(D647G) ΔendoMS-dnaE (D647G)
Transition A:T→G:C A→G 0.84 0.53 52 44 37 26 430 460
T→C 0.22 37 17 520
G:C→A:T G→A 0.57 0.80 33 47 24 39 360 330
C→T 1.04 62 56 310
Transversion A:T→C:G A→C 0.19 0.24 0.38 0.57 17 16 16 14
T→G 0.28 0.75 15 14
G:C→T:A G→T 0.16 0.20 - 0.16 11 14 11 14
C→A 0.25 0.20 17 21
A:T→T:A A→T 0.04 0.06 - <0.19 4.7 3.5 6.0 6.3
T→A 0.09 - 2.3 8.5
G:C→C:G G→C 0.07 0.08 - <0.16 0.39 1.0 6.0 4.5
C→G 0.09 - 1.7 4.1
Indels Deletion 0.06 <0.07 4.9 5.6
Insertion 0.04 <0.07 7.1 7.3
Overall 1.1 46 62 420

*Mutations are represented as that occurred in leading strand.