Figure 4.

Mitochondria-encoded mRNAs are more edited when they associate with mitoribosomes. (A) C-to-U editing levels calculated from total (RNA-seq) and ribosome-associated (Ribo-seq) RNA populations are presented. To identify potential variations in editing efficiencies, only sites that are partially edited and whose editing efficiencies is comprised between 10 and 90% in total RNAs were considered in the analysis. (B) Average editing levels of mitochondrial mRNAs were determined from both ribosome footprint and total RNA populations. The differences of editing levels calculated from both RNA samples (polysomal RNA—total RNA) are shown.