Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 1;46(12):5924–5934. doi: 10.1093/nar/gky382

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 8. — Effects of orientation on mRNA expression levels (A) and correlation (B). In systems where genes are convergently and divergently oriented SC builds up in the region between the genes causing correlations and altered gene expression (see SM for compositional details). (A) Average expression levels in time for many single trajectories showing a clear difference in mean expression levels as gene orientations are changed. (B) The mRNA correlation function between the two genes shows correlations change as a function of orientation. Gene and barrier lengths of 1 kb and 10 kb were used respectively. Correlation function computation are contained within the SM and the simulation parameters are the same as Figure 3.