Table 1.

Overall success (protocol-specified) for all groups.

Component	Nonrandomized SECURE-C (N = 89)	Randomized SECURE-C (N = 151)	Randomized ACDF (N = 140)	Posterior Probability		95% BCI* (Lower, Upper)
				Noninferiority	Superiority
NDI (≥25% improvement)	53/63 (84.1%)	113/125 (90.4%)	92/107 (86.0%)	100.0%	86.8%	(−3.6%, 13.3%)
No removals, etc.	61/65 (93.8%)	124/131 (94.7%)	102/121 (84.3%)	100.0%	99.6%	(2.4%, 16.9%)
No major complications	63/63 (100.0%)	125/125 (100.0%)	107/107 (100.0%)	100.0%	53.9%	(−2.2%, 2.7%)
Fusion (control)	N/A	N/A	101/104 (97.1%)	N/A	N/A	N/A
Overall success	53/65 (81.5%)	113/131 (86.3%)	84/120 (70.0%)	100.0%	99.9%	(6.3%, 25.8%)

Abbreviations: ACDF, anterior cervical discectomy and fusion; BCI, Bayesian credible intervals; NDI, neck disability index.

^*BCI for difference in proportions (SECURE-C − ACDF).