Fig.2.

Bri3 is decreased in postmortem hippocampus and temporal cortex of AD cases. Western blots analysis using the Bri3 BRICHOS₂ antibody against postmortem human hippocampus (A-D) and temporal cortex (E-H) from non-demented controls (hippocampus: n = 7; cortex: n = 8) and AD cases (hippocampus: n = 8; cortex: n = 5). Bri3 BRICHOS₂ reactivity was quantified for the 35 kDa (B,F) and 30 kDa (C,G) bands and normalized to actin levels. The 30 to 35 kDa ratio was calculated for each sample and compared between groups (D,H). ns, not significant; *p < 0.05.