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Bri2 and Bri3 interactions with Aβ/AβPP in CA1 region of hippocampus from tgAβPParc and AβPP –/– mice. PLA (red dots) for protein-protein interactions with (A-B) anti-Bri2 BRICHOS and anti-AβPP/Aβ antibodies (6E10); and (C-D) anti-Bri3 BRICHOS2 and anti-AβPP/Aβ antibodies (6E10). Images are representative of two to three independent experiments. Staining of nuclei is performed with DAPI (blue). Scale bars 20 μm.
