TABLE 3.
Clinical characteristics of NW, OW, OB, OW/T2DM, and OB/T2DM, subjects in the cross-sectional study
Charateristic | NW, n = 156 | OW, n = 71 | OB, n = 78 | OW/T2DM, n = 40 | OB/T2DM, n = 36 | Pa |
---|---|---|---|---|---|---|
Female/male | 100/56 | 46/25 | 39/39 | 18/22 | 20/16 | NS |
Age (yr) | 43 ± 11.2 | 46.2 ± 7.4 | 38.3 ± 11.9*,‡ | 56.9 ± 7.3*,‡ | 55.8 ± 8.9*,§ | <0.01 |
BMI (kg/m2) | 20.6 ± 0.9 | 26 ± 0.7* | 30.8 ± 3.4*,‡ | 26 ± 0.6*,‡ | 30.4 ± 3.8* | <0.01 |
SBP (mmHg) | 113.9 ± 10.8 | 115.8 ± 11.5 | 126.2 ± 17.8*,‡ | 135.1 ± 18.6*,‡ | 141.4 ± 24.8*,§ | <0.01 |
DBP (mmHg) | 71.2 ± 8 | 75.2 ± 7.8* | 78.3 ± 11.6* | 78.6 ± 12.4* | 86.4 ± 14.4*,§ | <0.01 |
TC (mM) | 4.2 ± 0.6 | 4.3 ± 0.5 | 4.7 ± 0.8*,‡ | 5.4 ± 0.9*,‡ | 5.5 ± 1*,§ | <0.01 |
TG (mM) | 0.8 ± 0.3 | 1 ± 0.3* | 1.6 ± 1.3*,‡ | 2.4 ± 1.5*,‡ | 2.2 ± 1.3*,§ | <0.01 |
HDL-c (mM) | 1.6 ± 0.3 | 1.4 ± 0.3* | 1.2 ± 0.3*,‡ | 1.3 ± 0.2*,‡ | 1.3 ± 0.3* | <0.01 |
LDL-c (mM) | 2.4 ± 0.5 | 2.6 ± 0.4* | 2.9 ± 0.6*,‡ | 3.3 ± 0.8*,‡ | 3.3 ± 0.8* | <0.01 |
FPG (mM) | 5 ± 0.4 | 5.1 ± 0.4* | 5.2 ± 0.5* | 8.2 ± 3*,‡ | 7.8 ± 2.1*,§ | <0.01 |
2hPG (mM) | 5.6 ± 1.1 | 5.8 ± 1.1 | 6.6 ± 1.5*,‡ | 15.1 ± 4.6*,‡ | 14.2 ± 4*,§ | <0.01 |
HbA1c (%) | 5.3 ± 0.3 | 5.4 ± 0.3 | 5.4 ± 0.4 | 7.2 ± 1.5*,‡ | 7 ± 1.1*,§ | <0.01 |
FIns (μU/ml) | 6 ± 2.7 | 8.4 ± 3.7* | 14.8 ± 14.5*,‡ | 9.7 ± 5* | 18.1 ± 25.1* | <0.01 |
2hIns (μU/ml) | 31.7 ± 20.2 | 36.2 ± 23.8 | 88.3 ± 73.4*,‡ | 64.2 ± 47.4*,‡ | 87.3 ± 66* | <0.01 |
HOMA-IR | 1.3 ± 0.6 | 1.9 ± 0.9* | 3.5 ± 4.1*,‡ | 3.4 ± 1.9*,‡ | 6.5 ± 10.6*,§ | <0.01 |
Matsuda ISI | 242.5 ± 161.3 | 178.1 ± 95.4* | 108.9 ± 76.9*,‡ | 71.3 ± 27.3*,‡ | 52.3 ± 23.3*,§ | <0.01 |
NS, not significant. aValues were calculated by Kruskal-Wallis H test. Data are means ± sd. *P < 0.01 vs. NW; ‡P < 0.01 vs. OW; §P < 0.01 vs. OB by the Mann-Whitney U test.