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. 2017 Sep 28;1(1):125–157. doi: 10.3233/ADR-170017

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© 2017 – IOS Press and the authors. All rights reserved

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Fig.5 — Overlaps between genes upregulated in the AD hippocampal transcriptome and those upregulated by viruses, interferon gamma or the viral mimic poly(I:C) in immunocompetent cells (MSigDB or GEO data). (X axis = virus| celltype|N upregulated genes from MSigDb or Geo): Y1 = N overlap; Y2 = p value. Tissue/cell abbreviations: A549, adenocarcinomic human alveolar basal epithelial cells; ABL, Akata Burkitt’s lymphoma cells; B2B/16HBE, BE(2)C or BEAS-2B, human bronchial epithelial cells; BroLav, human bronchial lavage; Calu-3, cultured human airway epithelial cells; DC, dendritic cells; GRE, glioma cell line; HAE, human airway epithelial cells; HBEC, human bronchial epithelial cells; HEK, human embryonic kidney cells; HeLa, cervical cancer cell line; HuH-7, hepatocarcinoma cell line; Macro, macrophage; Mgli, microglia; Mono, monocytes; NES, human nasal epithelial scrapings; NK, natural killer cells; PBMC, peripheral blood mononuclear cells; PLC/PRF/5 cells, human liver hepatoma cells; Trach epi, Tracheal epithelial cells. Viral abbreviations: HIV, human immunodeficiency virus; Cox B3, Coxsackie B3 virus; RSV, respiratory syncytial virus; LCMV, lymphocytic choriomeningitis virus; HMPV, human metapneumovirus; Ebola, Ebola virus; Influenza, Influenza A virus; Sendai, Sendai virus; HCoV, human coronavirus; IFNG, interferon gamma; SARS, severe acute respiratory syndrome coronavirus; HCMV, human cytomegalovirus; MCMV, mouse cytomegalovirus; Dhori, Dhori virus; EBV, Epstein-Barr virus; HepC, hepatitis C virus; KSHV, Kaposi’s sarcoma-associated herpesvirus; HSV-1, herpes simplex; Norwalk, Norwalk virus (Norovirus); Ad5, adenovirus 5; SIV, Simian immunodeficiency virus; poly(I:C), Polyinosinic:polycytidylic acid (a viral mimic stimulating TLR3 receptors); NDV, Newcastle disease virus; WestEq, Western equine encephalomyelitis virus; LASV, Lassa virus; dsRNA, double stranded RNA; HEV, hepatitis E virus.