Table 2.
Anal sphincter relaxation associated with SPWs, HAPW-SPWs and HAPWs.
| SPW amplitude (mmHg ± SD) | Anal sphincter amplitude before relaxation (mmHg ± SD) | Anal sphincter amplitude during relaxation (mmHg ± SD) | % of anal sphincter relaxation | Duration of anal sphincter relaxation (seconds) | |
|---|---|---|---|---|---|
| SPW (n = 124), 67% of total (n = 185) associated with anal sphincter relaxation | |||||
| Baseline (n = 52) | 18 ± 7.7 | 60.2 ± 20.6 | 31.25 ± 12.5 | 48.0 ± 8.8 | 15.6 ± 5.8 |
| Meal (n = 44) | 21.5 ± 9.5 ns | 65.6 ± 19.7 | 27.52 ± 9.16 | 57.2 ± 10.7∗∗∗ | 11.8 ± 4.2∗∗ |
| Bisacodyl (n = 24) | 25.3 ± 6.7∗∗ | 75.6 ± 19.9 | 25.9 ± 8.4 | 66.0 ± 7.1∗∗∗∗ | 14.8 ± 6.0 ns |
| Balloon (n = 4) | 24.5 ± 14.7 ns | 76.6 ± 16.2 | 42.8 ± 22.2 | 48.8 ± 12.2 ns | 12.3 ± 7.0 ns |
| HAPW-SPW (n = 51), 87.9 % of total (n = 58) associated with anal sphincter relaxation | |||||
| Baseline (n = 16) | 21.8 ± 6.1 | 70.8 ± 18.4 | 31.2 ± 13 | 55.8 ± 11.6 | 19.6 ± 7.7 |
| Meal (n = 16) | 24.4 ± 7.1ns | 84.5 ± 29.5 | 30.3 ± 12.6 | 63.4 ± 9.2∗ | 18 ± 9.3 ns |
| Bisacodyl (n = 15) | 29.4 ± 12 ns | 83 ± 25.2 | 24.3 ± 9.6 | 70.6 ± 7.1∗∗∗ | 16 ± 7.55 ns |
| Balloon (n = 4) | 16.4 ± 16 ns | 72.7 ± 6.40 | 26.6 ± 16 | 62.8 ± 16.6 ns | 21.2 ± 3 ns |
| HAPW (n = 20), 46.5% of total (n = 43) associated with anal sphincter relaxation | |||||
| Baseline (n= 6) | 119.4 ± 37.2 | 72.0 ± 18.6 | 35.9 ± 12.3 | 50.2 ± 10.4 | 20.3 ± 7.5 |
| Meal (n = 3) | 120.3 ± 16.8 ns | 65.7 ± 12.7 | 29.2 ± 9 | 56.0 ± 5.3 ns | 6.3 ± 4.1∗ |
| Bisacodyl (n = 8) | 207.0 ± 51.0∗∗ | 82.2 ± 11.0 | 27.2 ± 10.4 | 67.3 ± 10.2 ∗ | 22.6 ± 10.8 ns |
| Balloon (n = 3) | 129.0 ± 33.5 ns | 86.6 ± 19.0 | 29.2 ± 9.0 | 46.1 ± 11.3 ns | 9.6 ± 8.9∗ |
All compared with their baseline conditions ns P > 0.05; ∗P ≤ 0.05; ∗∗P ≤ 0.01; ∗∗∗P ≤ 0.001; ∗∗∗∗P ≤ 0.0001.