Table 2.

Results of office blood pressure measurements in patients with rs1045642 ABCB1 polymorphisms undergoing amlodipine therapy

	CC (n=17)		CT (n=53)		TT (n=30)
	Baseline	12 weeks	Baseline	12 weeks	Baseline	12 weeks
Office SBP (mmHg)	146.9±8.39	139.65±6.26	147.65±7.25	139.00±5.36	148.92±8.28	139.99±6.98
Δ (mmHg)	−7.25±3.34		−8.65±3.39		−8.93±3.19
Δ (%)	−4.94±2.91		−5.86±2.12		−6.00±2.20
P, intragroup	0.04		0.02		0.02
Office DBP (mmHg)	89.51±7.94	83.04±6.38	87.83±6.92	80.23±5.76	85.22±7.35	76.85±6.06
Δ (mmHg)	−6.47±1.62		−7.60±2.46		−8.37±1.53
Δ (%)	−7.23±1.23		−8.65±2.40		−9.82±2.74
P, intragroup	0.02		0.04		0.04
Clinical HR (beats/min)	74.52±5.12	71.10±5.03	71.31±5.16	69.01±4.76	72.93±7.52	69.86±5.94
Δ (beats/min)	−3.42±0.82		−2.30±0.46		−3.07±0.70
Δ (%)	−4.59±0.22		−3.22±0.32		−4.21±0.50
P, intragroup	0.6		0.2		0.6

Note: Data are reported as mean ± SD.

Abbreviation: HR, heart rate.